D78 Neoplasm digest benign/uncertain (ICD-10:D37.9)

June 6, 2024

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Introduction

Neoplasm digest benign/uncertain refers to the presence of abnormal growths or tumors that are non-cancerous or of uncertain nature. These neoplasms can occur in various parts of the body and may cause symptoms or remain asymptomatic. The aim of this guide is to provide a comprehensive overview of the condition, including symptoms, causes, diagnostic steps, possible interventions, and patient education.[1][2]

Codes

  • ICPC-2 Code: D78 Neoplasm digest benign/uncertain[3]
  • ICD-10 Code: D37.9 Neoplasm of uncertain or unknown behaviour of digestive organ, unspecified[4]

Symptoms

  • Abnormal growth or lump in the affected area[5]
  • Pain or discomfort in the affected area[6]
  • Changes in bowel or bladder habits
  • Unexplained weight loss[7]
  • Fatigue or weakness[8]

Causes

  • Genetic factors[9]
  • Environmental factors
  • Hormonal imbalances
  • Immune system dysfunction
  • Exposure to certain chemicals or toxins[10]

Diagnostic Steps

Medical History

  • Gather information about the patient’s family history of neoplasms or cancer
  • Identify any risk factors, such as smoking, exposure to radiation, or previous cancer treatments
  • Assess the patient’s overall health and any pre-existing medical conditions

Physical Examination

  • Perform a thorough physical examination to assess the size, location, and characteristics of the neoplasm
  • Check for any signs of metastasis or spread of the neoplasm to other parts of the body
  • Evaluate the patient’s general health and well-being

Laboratory Tests

  • Complete blood count (CBC) to assess for any abnormalities or signs of infection
  • Tumor marker tests to measure specific substances in the blood that may indicate the presence of a neoplasm
  • Biopsy of the neoplasm to obtain a tissue sample for further analysis

Diagnostic Imaging

  • X-rays to visualize the neoplasm and assess its size and location
  • Ultrasound to evaluate the neoplasm and surrounding tissues
  • CT scans or MRIs to obtain detailed images of the neoplasm and its extent
  • PET scans to determine if the neoplasm is cancerous or benign

Other Tests

  • Endoscopy or colonoscopy to visualize neoplasms in the digestive tract
  • Genetic testing to identify any specific genetic mutations or abnormalities
  • Fine needle aspiration or core needle biopsy to obtain tissue samples for analysis

Follow-up and Patient Education

  • Schedule regular follow-up appointments to monitor the neoplasm and assess any changes or progression
  • Educate the patient about the nature of the neoplasm, its potential risks, and available treatment options
  • Provide resources and support for the patient to cope with the emotional and physical challenges associated with neoplasms

Possible Interventions

Traditional Interventions

Medications:

Top 5 drugs for Neoplasm Digest Benign/Uncertain:

  1. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (e.g., Ibuprofen, Naproxen):
    • Cost: Generic versions can be $3-$20/month.
    • Contraindications: History of gastrointestinal bleeding, kidney disease.
    • Side effects: Upset stomach, increased risk of bleeding.
    • Severe side effects: Kidney damage, allergic reactions.
    • Drug interactions: Blood thinners, certain antidepressants.
    • Warning: Prolonged use may increase the risk of cardiovascular events.
  2. Corticosteroids (e.g., Prednisone, Dexamethasone):
    • Cost: Generic versions can be $4-$30/month.
    • Contraindications: Active infections, uncontrolled diabetes.
    • Side effects: Increased appetite, weight gain, mood changes.
    • Severe side effects: Increased risk of infections, osteoporosis.
    • Drug interactions: Nonsteroidal anti-inflammatory drugs (NSAIDs), certain anticoagulants.
    • Warning: Long-term use may require gradual tapering to avoid adrenal insufficiency.
  3. Hormone Therapy (e.g., Tamoxifen, Leuprolide):
    • Cost: Varies depending on the specific medication.
    • Contraindications: Pregnancy, history of blood clots.
    • Side effects: Hot flashes, mood changes, vaginal dryness.
    • Severe side effects: Increased risk of uterine cancer, blood clots.
    • Drug interactions: Certain antidepressants, blood thinners.
    • Warning: Regular monitoring of hormone levels and potential side effects is necessary.
  4. Immunotherapy (e.g., Pembrolizumab, Nivolumab):
    • Cost: Varies depending on the specific medication.
    • Contraindications: Severe autoimmune diseases, active infections.
    • Side effects: Fatigue, skin rash, flu-like symptoms.
    • Severe side effects: Severe allergic reactions, organ damage.
    • Drug interactions: Certain immunosuppressive medications.
    • Warning: Regular monitoring of immune function and potential side effects is necessary.
  5. Chemotherapy (e.g., Paclitaxel, Doxorubicin):
    • Cost: Varies depending on the specific medication.
    • Contraindications: Severe bone marrow suppression, active infections.
    • Side effects: Nausea, hair loss, fatigue.
    • Severe side effects: Suppression of bone marrow function, increased risk of infections.
    • Drug interactions: Certain medications that affect liver function.
    • Warning: Regular monitoring of blood counts and potential side effects is necessary.

Alternative Drugs:

  • Targeted Therapy (e.g., Trastuzumab, Imatinib): Medications that specifically target certain genetic mutations or proteins involved in neoplastic growth.
  • Radiopharmaceuticals (e.g., Iodine-131, Samarium-153): Radioactive substances used to target and destroy neoplastic cells.
  • Angiogenesis Inhibitors (e.g., Bevacizumab, Ramucirumab): Medications that inhibit the formation of new blood vessels, thereby limiting the blood supply to neoplastic cells.
  • Immunomodulators (e.g., Interferon-alpha, Interleukin-2): Medications that enhance the body’s immune response against neoplastic cells.
  • Antiemetics (e.g., Ondansetron, Metoclopramide): Medications used to control nausea and vomiting associated with chemotherapy or radiation therapy.

Surgical Procedures:

  • Excisional Biopsy: Surgical removal of the neoplasm for further analysis. Cost: $1,000 to $5,000.
  • Lumpectomy: Surgical removal of the neoplasm and a small portion of surrounding healthy tissue. Cost: $5,000 to $10,000.
  • Mastectomy: Surgical removal of the breast tissue containing the neoplasm. Cost: $10,000 to $20,000.
  • Lymph Node Dissection: Surgical removal of nearby lymph nodes to assess for spread of the neoplasm. Cost: $5,000 to $10,000.
  • Cryosurgery: Freezing the neoplasm to destroy abnormal cells. Cost: $1,000 to $5,000.

Alternative Interventions

  • Acupuncture: May help alleviate pain and improve overall well-being. Cost: $60-$120 per session.
  • Herbal Supplements: Some herbal supplements, such as green tea extract or turmeric, may have potential anti-cancer properties. Cost: Varies depending on the specific supplement.
  • Mind-Body Techniques: Practices like meditation, yoga, or guided imagery may help reduce stress and improve quality of life. Cost: Varies depending on the specific practice.
  • Dietary Modifications: Following a healthy, balanced diet rich in fruits, vegetables, and whole grains may help support overall health and immune function. Cost: Varies depending on individual food choices.
  • Physical Activity: Regular exercise has been associated with a reduced risk of certain types of neoplasms. Cost: Varies depending on individual preferences and access to exercise facilities.

Lifestyle Interventions

  • Smoking Cessation: Quitting smoking can significantly reduce the risk of developing neoplasms. Cost: Varies depending on individual methods used (e.g., nicotine replacement therapy, counseling).
  • Healthy Weight Management: Maintaining a healthy weight through a balanced diet and regular exercise may help reduce the risk of neoplasms. Cost: Varies depending on individual food choices and access to exercise facilities.
  • Sun Protection: Using sunscreen, wearing protective clothing, and avoiding excessive sun exposure can help prevent skin neoplasms. Cost: Varies depending on the cost of sunscreen and protective clothing.
  • Limiting Alcohol Consumption: Excessive alcohol consumption has been linked to an increased risk of certain types of neoplasms. Cost: Varies depending on individual alcohol consumption habits.
  • Stress Management: Engaging in stress-reducing activities, such as meditation or relaxation techniques, may help support overall health and well-being. Cost: Varies depending on the specific practice or activity.

It is important to note that the cost ranges provided are approximate and may vary depending on the location and availability of the interventions. It is recommended to consult with a healthcare professional for personalized treatment options and cost estimates.

Mirari Cold Plasma Alternative Intervention

Understanding Mirari Cold Plasma

  • Safe and Non-Invasive Treatment: Mirari Cold Plasma is a safe and non-invasive treatment option for various skin conditions. It does not require incisions, minimizing the risk of scarring, bleeding, or tissue damage.
  • Efficient Extraction of Foreign Bodies: Mirari Cold Plasma facilitates the removal of foreign bodies from the skin by degrading and dissociating organic matter, allowing easier access and extraction.
  • Pain Reduction and Comfort: Mirari Cold Plasma has a local analgesic effect, providing pain relief during the treatment, making it more comfortable for the patient.
  • Reduced Risk of Infection: Mirari Cold Plasma has antimicrobial properties, effectively killing bacteria and reducing the risk of infection.
  • Accelerated Healing and Minimal Scarring: Mirari Cold Plasma stimulates wound healing and tissue regeneration, reducing healing time and minimizing the formation of scars.

Mirari Cold Plasma Prescription

Video instructions for using Mirari Cold Plasma Device – D78 Neoplasm digest benign/uncertain (ICD-10:D37.9)

MildModerateSevere
Mode setting: 1 (Infection)
Location: 3 (Kidney, Liver & Spleen)
Morning: 15 minutes,
Evening: 15 minutes
Mode setting: 1 (Infection)
Location: 3 (Kidney, Liver & Spleen)
Morning: 30 minutes,
Lunch: 30 minutes,
Evening: 30 minutes
Mode setting: 1 (Infection)
Location: 3 (Kidney, Liver & Spleen)
Morning: 30 minutes,
Lunch: 30 minutes,
Evening: 30 minutes
Mode setting: 2 (Wound Healing)
Location: 3 (Kidney, Liver & Spleen)
Morning: 15 minutes,
Evening: 15 minutes
Mode setting: 2 (Wound Healing)
Location: 3 (Kidney, Liver & Spleen)
Morning: 30 minutes,
Lunch: 30 minutes,
Evening: 30 minutes
Mode setting: 2 (Wound Healing)
Location: 3 (Kidney, Liver & Spleen)
Morning: 30 minutes,
Lunch: 30 minutes,
Evening: 30 minutes
Mode setting: 3 (Antiviral Therapy)
Location: 2 (Prostate & Uterus)
Morning: 15 minutes,
Evening: 15 minutes
Mode setting: 3 (Antiviral Therapy)
Location: 2 (Prostate & Uterus)
Morning: 30 minutes,
Lunch: 30 minutes,
Evening: 30 minutes
Mode setting: 3 (Antiviral Therapy)
Location: 2 (Prostate & Uterus)
Morning: 30 minutes,
Lunch: 30 minutes,
Evening: 30 minutes
Mode setting: 7 (Immunotherapy)
Location: 4 (Heart, Bile & Pancreas)
Morning: 15 minutes,
Evening: 15 minutes
Mode setting: 7 (Immunotherapy)
Location: 4 (Heart, Bile & Pancreas)
Morning: 30 minutes,
Lunch: 30 minutes,
Evening: 30 minutes
Mode setting: 7 (Immunotherapy)
Location: 4 (Heart, Bile & Pancreas)
Morning: 30 minutes,
Lunch: 30 minutes,
Evening: 30 minutes
Total
Morning: 60 minutes approx. $10 USD,
Evening: 60 minutes approx. $10 USD
Total
Morning: 120 minutes approx. $20 USD,
Lunch: 120 minutes approx. $20 USD,
Evening: 120 minutes approx. $20 USD,
Total
Morning: 120 minutes approx. $20 USD,
Lunch: 120 minutes approx. $20 USD,
Evening: 120 minutes approx. $20 USD,
Usual treatment for 7-60 days approx. $140 USD $1200 USDUsual treatment for 6-8 weeks approx. $2,520 USD $3,360 USD
Usual treatment for 3-6 months approx. $5,400 USD $10,800 USD
Location note miraridoctor 1
  • Localized (0)
  • Sacrum (1)
  • Prostate & Uterus (2)
  • Kidney, Liver & Spleen (3)
  • Heart, Bile & Pancreas (4)
  • Lungs (5)
  • Throat, Lymphatic & Thyroid (6)
  • Neuro system & ENT (7)

Use the Mirari Cold Plasma device to treat Neoplasm digest benign/uncertain effectively.

WARNING: MIRARI COLD PLASMA IS DESIGNED FOR THE HUMAN BODY WITHOUT ANY ARTIFICIAL OR THIRD PARTY PRODUCTS. USE OF OTHER PRODUCTS IN COMBINATION WITH MIRARI COLD PLASMA MAY CAUSE UNPREDICTABLE EFFECTS, HARM OR INJURY. PLEASE CONSULT A MEDICAL PROFESSIONAL BEFORE COMBINING ANY OTHER PRODUCTS WITH USE OF MIRARI.

Step 1: Cleanse the Skin

  • Start by cleaning the affected area of the skin with a gentle cleanser or mild soap and water. Gently pat the area dry with a clean towel.

Step 2: Prepare the Mirari Cold Plasma device

  • Ensure that the Mirari Cold Plasma device is fully charged or has fresh batteries as per the manufacturer’s instructions. Make sure the device is clean and in good working condition.
  • Switch on the Mirari device using the power button or by following the specific instructions provided with the device.
  • Some Mirari devices may have adjustable settings for intensity or treatment duration. Follow the manufacturer’s instructions to select the appropriate settings based on your needs and the recommended guidelines.

Step 3: Apply the Device

  • Place the Mirari device in direct contact with the affected area of the skin. Gently glide or hold the device over the skin surface, ensuring even coverage of the area experiencing.
  • Slowly move the Mirari device in a circular motion or follow a specific pattern as indicated in the user manual. This helps ensure thorough treatment coverage.

Step 4: Monitor and Assess:

  • Keep track of your progress and evaluate the effectiveness of the Mirari device in managing your Neoplasm digest benign/uncertain. If you have any concerns or notice any adverse reactions, consult with your health care professional.

Note

This guide is for informational purposes only and should not replace the advice of a medical professional. Always consult with your healthcare provider or a qualified medical professional for personal advice, diagnosis, or treatment. Do not solely rely on the information presented here for decisions about your health. Use of this information is at your own risk. The authors of this guide, nor any associated entities or platforms, are not responsible for any potential adverse effects or outcomes based on the content.

Mirari Cold Plasma System Disclaimer

  • Purpose: The Mirari Cold Plasma System is a Class 2 medical device designed for use by trained healthcare professionals. It is registered for use in Thailand and Vietnam. It is not intended for use outside of these locations.
  • Informational Use: The content and information provided with the device are for educational and informational purposes only. They are not a substitute for professional medical advice or care.
  • Variable Outcomes: While the device is approved for specific uses, individual outcomes can differ. We do not assert or guarantee specific medical outcomes.
  • Consultation: Prior to utilizing the device or making decisions based on its content, it is essential to consult with a Certified Mirari Tele-Therapist and your medical healthcare provider regarding specific protocols.
  • Liability: By using this device, users are acknowledging and accepting all potential risks. Neither the manufacturer nor the distributor will be held accountable for any adverse reactions, injuries, or damages stemming from its use.
  • Geographical Availability: This device has received approval for designated purposes by the Thai and Vietnam FDA. As of now, outside of Thailand and Vietnam, the Mirari Cold Plasma System is not available for purchase or use.

References

  1. Healthline. (2023). Neoplastic Disease: Causes, Types, Symptoms, and Treatment. Retrieved from https://www.healthline.com/health/neoplastic-disease
  2. BMJ Open. (2020). Appendix 4: ICPC2 codes registered in the study. Retrieved from https://bmjopen.bmj.com/content/bmjopen/10/9/e037664/DC4/embed/inline-supplementary-material-4.pdf?download=true
  3. AAPC. (n.d.). ICD-10 Code for Neoplasm of uncertain behavior of digestive organ, unspecified (D37.9). Retrieved from https://www.aapc.com/codes/icd-10-codes/D37.9
  4. ICD10Data.com. (n.d.). Neoplasm of uncertain behavior of oral cavity and digestive organs (D37). Retrieved from https://www.icd10data.com/ICD10CM/Codes/C00-D49/D37-D48/D37-
  5. Cleveland Clinic. (2021). Benign Tumor: Definition, Types, Causes & Management. Retrieved from https://my.clevelandclinic.org/health/diseases/22121-benign-tumor
  6. Vinmec. (n.d.). Are the results of the diagnosis of benign tumors worrisome? Retrieved from https://www.vinmec.com/en/news/health-news/what-should-we-do-when-we-are-diagnosed-with-a-benign-tumor/
  7. Healthline. (2023). Benign Tumors: Causes, Types, Symptoms, Diagnosis, Treatment. Retrieved from https://www.healthline.com/health/benign
  8. YouTube. (2023). Neoplasm, Causes, Signs and Symptoms, Diagnosis and Treatment. Retrieved from https://www.youtube.com/watch?v=VqpJlwrgWes
  9. National Cancer Institute. (n.d.). What Causes Benign Tumors? Retrieved from https://www.cancer.gov/about-cancer/causes-prevention/risk/benign-tumors
  10. American Cancer Society. (2022). Benign Tumors. Retrieved from https://www.cancer.org/cancer/cancer-causes/general-info/benign-tumors.html
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