Weaning Off Topical Steroids: A Guide to Safe Steroid Withdrawal

July 1, 2024

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If you’ve been using topical corticosteroids to manage a skin condition like eczema, you may have heard about the potential risks of long-term use. One of these risks is developing topical steroid withdrawal (TSW), also known as red skin syndrome or steroid addiction. TSW can cause uncomfortable symptoms like burning, stinging, and itching, along with a worsening rash.

But don’t panic – weaning off topical steroids under the guidance of a dermatologist can help you avoid or manage TSW while keeping your skin healthy. In this article, we’ll debunk some common myths about topical steroid withdrawal, discuss the signs and symptoms to watch for, and provide a step-by-step guide to tapering off steroid creams safely.

First, let’s review some basics about topical steroids and how they work. Topical corticosteroids are anti-inflammatory medications applied directly to the skin to treat various conditions such as eczema, psoriasis, and contact dermatitis. They come in different strengths, from mild over-the-counter hydrocortisone to very potent prescription creams.

Topical steroids work by reducing inflammation, redness, and itching in the skin. They do this by binding to glucocorticoid receptors in skin cells, which suppresses the immune system and narrows blood vessels in the area[1]. When used as directed in short bursts, topical steroids are very effective and safe for most people.

However, problems can arise with prolonged, frequent use of moderate- to high-potency steroids, especially on delicate areas like the face and genitals. Over time, the skin can develop a tolerance to the medication, requiring higher and higher doses to achieve the same results. The skin may also become dependent on the steroids to function normally.

When someone abruptly stops using topical steroids after a long period of use, they may experience topical steroid withdrawal. TSW is thought to occur because the skin’s natural steroid production (via the hypothalamic-pituitary-adrenal or HPA axis) has been suppressed and needs time to recover[2]. In the meantime, the skin can flare up with redness, itching, burning, and peeling as it adjusts to the lack of topical steroids.

Not everyone who uses topical steroids long-term will develop TSW, but certain factors may increase the risk. These include:

  • Using high-potency steroids
  • Applying steroids to sensitive areas like the face, genitals, or skin folds
  • Frequent use (daily or more) for longer than 2-4 weeks
  • Applying more steroid than directed
  • Stopping steroids suddenly rather than tapering off
  • Having a history of eczema or sensitive skin

If you’re concerned about TSW, the first step is to talk to your dermatologist. They can assess your skin, review your steroid use, and recommend the best course of action. In most cases, gradually tapering off topical steroids under medical supervision can help minimize TSW symptoms while keeping eczema or other conditions under control.

Myths and Facts About Topical Steroid Withdrawal

There’s a lot of information (and misinformation) out there about TSW. Let’s clear up some common myths:

Myth: Topical steroid withdrawal is a sign of “steroid addiction.”

Fact: TSW is sometimes called “steroid addiction,” but this isn’t entirely accurate. Addiction involves cravings and compulsive use of a substance despite negative consequences. With TSW, the body has developed a physical dependence on topical steroids, but not an addiction[1].

The term “addiction” can also imply a moral failing or lack of willpower. In reality, TSW is a medical condition that can happen to anyone using topical steroids, even when following a doctor’s instructions. There’s no shame in developing TSW or seeking help for it.

Myth: Topical steroid withdrawal means your skin is “damaged” or “weak.”

Fact: While TSW can certainly make skin appear red, flaky, and fragile, these symptoms are usually temporary and not a sign of permanent damage. With time and proper care, skin can recover its normal strength and appearance after TSW.

Keep in mind that the symptoms of TSW can mimic those of eczema or the original skin condition. It’s important to work with a dermatologist to distinguish a normal flare-up from steroid-induced issues. Proper treatment can promote skin healing.

Myth: You can never use topical steroids again if you’ve had TSW.

Fact: Having TSW once doesn’t necessarily mean you can never use topical steroids again. However, you may need to be more cautious with them to prevent another withdrawal reaction. Some strategies include:

  • Using only low-potency steroids
  • Applying steroids less frequently (a few times per week vs. daily)
  • Treating only small areas at a time
  • Taking regular breaks from steroid use
  • Relying more on steroid-sparing therapies like moisturizers and topical calcineurin inhibitors

Your dermatologist can help you develop a personalized plan for if and how to incorporate topical steroids into your long-term skin care regimen. Don’t be afraid to ask questions and advocate for your health.

Myth: Topical steroid withdrawal is contagious.

Fact: You cannot “catch” TSW from someone else. It is an individual reaction to stopping topical corticosteroids and does not spread by contact, sharing towels, etc. However, open sores from TSW can become infected, so it’s important to practice good hygiene and wound care.

Myth: There’s nothing you can do to treat topical steroid withdrawal.

Fact: While there’s no instant cure for TSW, there are many ways to manage symptoms and support skin healing. Working closely with a dermatologist is key to developing an appropriate treatment plan, which may include:

  • Gradually tapering topical steroid doses
  • Using emollients and gentle cleansers to repair the skin barrier
  • Applying cool compresses to relieve itching and burning
  • Taking oral antihistamines or pain relievers as needed
  • Using topical calcineurin inhibitors like tacrolimus or pimecrolimus
  • Trying phototherapy (light therapy) to calm inflammation
  • Addressing skin infections with topical or oral antibiotics
  • Managing stress and sleep disturbances
  • Connecting with TSW support communities

Healing from TSW is possible, but it takes patience and persistence. With proper medical guidance and self-care, most people see symptoms start to improve within a few weeks to a few months after stopping steroids. Full recovery can take several months to a few years in severe cases. Remember, everyone’s timeline is different.

Signs and Symptoms of Topical Steroid Withdrawal

Topical steroid withdrawal can cause a range of skin and full-body symptoms[3]. The severity and duration of symptoms vary from person to person, but may include:

  • Red skin syndrome: This is the hallmark of TSW. The skin becomes bright red, swollen, and hot to the touch, often in areas where steroids were applied. The redness may spread to other parts of the body as well.
  • Itching: Intense itching is common during TSW. It can feel deep and painful, disrupting sleep and daily activities. Scratching can lead to further skin damage and infection.
  • Burning or stinging: The skin may feel like it’s burning or has a pins-and-needles sensation. This can be very uncomfortable, especially when the skin is touched or exposed to water, heat, or sweat.
  • Oozing and crusting: Skin affected by TSW may ooze clear fluid or pus and develop yellowish crusts. Oozing is a sign of a compromised skin barrier and can increase the risk of infection.
  • Flaking and peeling: As skin inflammation starts to subside, the outer layers of skin may shed excessively. This is part of the healing process, but it can be messy and uncomfortable.
  • Skin thickening: Prolonged steroid use can cause the skin to become thinner and more fragile. During TSW, the skin may rebound and become thicker than normal, with a rough, leathery texture. This is temporary and will improve with time.
  • Skin sensitivity: TSW can make skin more sensitive to heat, cold, friction, and irritants like fragrances or harsh soaps. Wearing soft, breathable fabrics and using gentle, fragrance-free products can help minimize discomfort.
  • Edema: Some people with TSW develop swelling (edema) in the affected areas or in the hands, feet, or ankles. This is thought to be due to blood vessel dilation and fluid retention. Elevating the limbs and using compression garments may provide relief.
  • Skin infections: Open sores and cracks in the skin from TSW can allow bacteria to enter and cause infections. Signs of infection include increased redness, swelling, pain, warmth, pus, odor, fever, or red streaks extending from the area. Infections require prompt medical treatment.
  • Thermoregulation issues: TSW can disrupt the skin’s ability to regulate body temperature, leading to feeling hot or cold, sweating excessively, or shivering. Dressing in layers and keeping the environment cool can help manage these symptoms.
  • Fatigue and insomnia: The physical and emotional stress of TSW can cause profound fatigue and sleep disturbances. Itching and discomfort may keep you up at night, while inflammation itself can be exhausting. Prioritizing rest and stress relief is important for coping and healing.
  • Psychological effects: The visible skin changes and relentless symptoms of TSW can take a toll on mental health. Many people with TSW experience anxiety, depression, irritability, and social isolation. Seeking support from loved ones, mental health professionals, and TSW communities can help you weather the tough times.

It’s important to note that not everyone with TSW will experience all of these symptoms, and the severity can vary over the course of the withdrawal process. Keeping a symptom diary and working closely with your dermatologist can help you track your progress and adjust your treatment plan as needed.

If you suspect you may be experiencing TSW, don’t hesitate to reach out for medical help. TSW can be a challenging and isolating experience, but you don’t have to go through it alone. With proper support and management, it is possible to get through withdrawal and achieve healthy, resilient skin on the other side.

How to Taper Off Topical Steroids Safely

If you and your dermatologist have determined that weaning off topical steroids is appropriate for managing or preventing TSW, the next step is to develop a personalized topical steroid withdrawal plan. This typically involves gradually reducing your steroid dose over a period of weeks to months, depending on the potency of the steroid and how long you’ve been using it.

Tapering steroids too quickly can trigger or worsen TSW symptoms, while tapering too slowly can prolong steroid exposure and dependence. Finding the right balance requires close medical supervision and adjusting the plan as needed based on your skin’s response. Here are some general principles to keep in mind:

Start with the lowest effective dose.

If you’ve been using a high-potency steroid, your dermatologist may recommend stepping down to a lower potency version before starting the taper. For example, you might transition from a Class 1 (super potent) steroid like clobetasol propionate 0.05% to a Class 3 (potent) steroid like triamcinolone acetonide 0.1%[4].

The goal is to find the minimum steroid dose that still controls your symptoms, so you have room to taper further as your skin adjusts. Be patient with the process and don’t try to rush it.

Reduce the frequency of application.

Once you’re on the lowest effective dose, start spacing out your steroid applications. Instead of applying the cream or ointment daily, try every other day for a week or two. If your skin tolerates this, you can then reduce to twice weekly, then once weekly, and so on.

Keep in mind that it’s common to have some increased redness, itching, or flaking during this process as your skin adapts to less frequent steroid use. These flares are usually temporary and not a sign that the taper isn’t working. Stick with it and use other therapies like moisturizers, cool compresses, or antihistamines to manage symptoms in the meantime.

Transition to steroid-sparing therapies.

As you taper off topical steroids, it’s important to incorporate other treatments that can help control inflammation and support skin healing. Some options include:

  • Emollients and moisturizers: Applying a thick, fragrance-free cream or ointment several times a day can help soothe irritated skin, reduce itching and flaking, and restore the skin barrier. Look for products with ingredients like ceramides, hyaluronic acid, or colloidal oatmeal.
  • Topical calcineurin inhibitors (TCIs): Medications like tacrolimus and pimecrolimus can be effective alternatives to steroids for managing eczema and TSW. They work by suppressing the immune system in the skin and are generally safer for long-term use on the face and sensitive areas[5].
  • Wet wraps: Applying topical medications or moisturizers under a layer of damp gauze or clothing can help them penetrate the skin more effectively and provide a physical barrier against scratching. Wet wraps can be especially soothing for intense itching or burning.
  • Phototherapy: Controlled exposure to ultraviolet (UV) light can help calm skin inflammation and itching. Narrowband UVB and UVA1 are the most common types of phototherapy used for eczema and TSW[6]. This treatment is usually done in a dermatologist’s office or with a home phototherapy unit.
  • Stress management: Stress is a common trigger for eczema and can exacerbate TSW symptoms. Engaging in relaxation techniques like deep breathing, meditation, yoga, or tai chi can help lower stress levels and promote skin healing. Regular exercise, adequate sleep, and social support are also important for managing stress.

Work with your dermatologist to develop a comprehensive treatment plan that incorporates a mix of these therapies to help you safely taper off topical steroids and manage TSW symptoms.

Adjust the plan as needed.

Tapering off topical steroids is not a linear process. You may find that you need to adjust your taper schedule based on how your skin responds. For example, if you experience a severe flare after reducing your steroid dose, your dermatologist may recommend going back up to the previous dose for a while before attempting to taper again.

It’s also important to be flexible with your treatment plan and willing to try new approaches if something isn’t working. What helps one person with TSW may not work for another. Don’t hesitate to communicate openly with your dermatologist about your symptoms, concerns, and preferences.

Remember, the goal of tapering is to minimize TSW symptoms while still effectively managing your underlying skin condition. It may take some trial and error to find the right balance, but with patience and persistence, it is possible to successfully wean off topical steroids and achieve healthier skin.

Coping with TSW Symptoms

As you navigate the process of weaning off topical steroids, you may experience a range of uncomfortable symptoms like itchingburningredness, and flaking. While these symptoms can be frustrating and distressing, there are many coping strategies and self-care practices that can help you find relief and promote skin healing. Here are some tips:

Manage the itch.

Intense itching is one of the most common and maddening symptoms of TSW. Scratching may provide temporary relief, but it can also damage the skin barrier, leading to increased inflammation, pain, and risk of infection. Instead of scratching, try these alternative strategies for managing the itch:

  • Apply a cool compress or take a lukewarm bath to soothe the skin.
  • Use a gentle, fragrance-free moisturizer to keep the skin hydrated and reduce itching.
  • Try an over-the-counter anti-itch cream containing pramoxine, menthol, or capsaicin.
  • Take an oral antihistamine like diphenhydramine or cetirizine to reduce itching from the inside out.
  • Wear loose, breathable clothing to minimize friction and irritation.
  • Keep your nails short and your hands clean to reduce damage if you do scratch.
  • Distract yourself with activities that keep your hands busy, like puzzles, knitting, or video games.
  • Practice relaxation techniques like deep breathing or meditation to calm the itch-scratch cycle.

If the itching is severe or interfering with your sleep and daily activities, talk to your dermatologist about prescription options like gabapentin, naltrexone, or phototherapy.

Soothe the burn.

Burning and stinging sensations are another hallmark of TSW, especially in the early stages of withdrawal. These symptoms can be triggered by heat, sweat, friction, or contact with irritants. To soothe the burn and protect your skin:

  • Take a lukewarm bath or apply a cool compress to the affected areas.
  • Use a gentle, non-foaming cleanser to avoid stripping the skin of its natural oils.
  • Apply a thick, fragrance-free emollient or balm to create a protective barrier on the skin.
  • Avoid hot showers, saunas, or other sources of heat that can exacerbate burning.
  • Wear soft, breathable fabrics like cotton or bamboo to minimize friction.
  • Use a humidifier to add moisture to the air and prevent skin dryness.
  • Try a topical calcineurin inhibitor like tacrolimus or pimecrolimus to calm inflammation.
  • Take an over-the-counter pain reliever like acetaminophen or ibuprofen if needed.

If the burning is severe or accompanied by other signs of infection like swelling, oozing, or fever, contact your dermatologist right away.

Manage flaking and peeling.

As the skin inflammation of TSW starts to subside, you may notice an increase in flaking and peeling. This is a sign that the skin is starting to heal and shed its damaged outer layers. While it can be tempting to pick or peel the flakes, it’s important to let the skin shed naturally to avoid further irritation. Here are some tips for managing flaking and promoting healthy skin turnover:

  • Gently exfoliate the skin with a soft washcloth or konjac sponge to remove loose flakes.
  • Apply a thick, occlusive moisturizer like petroleum jelly or shea butter to soften and protect the skin.
  • Use a humidifier to add moisture to the air and prevent skin dryness.
  • Avoid harsh soaps, alcohol-based products, or exfoliating scrubs that can irritate the skin.
  • Drink plenty of water and eat a balanced diet rich in skin-supporting nutrients like vitamin C, vitamin E, and omega-3 fatty acids.
  • Consider taking an oral vitamin D supplement to support skin cell turnover and immune function.
  • Be patient and allow the skin to heal at its own pace, which can take several weeks to several months.

If the flaking and peeling are accompanied by redness, itching, or burning, you may be experiencing a TSW flare. Contact your dermatologist for guidance on adjusting your treatment plan.

Prevent infection.

The open sores and cracks in the skin caused by TSW can provide an entry point for bacteria, leading to secondary infections. To reduce your risk of infection and promote skin healing:

  • Wash your hands frequently, especially before touching your face or applying skincare products.
  • Keep your skin clean and moisturized to support its natural barrier function.
  • Apply a fragrance-free, non-comedogenic moisturizer to damp skin to lock in hydration.
  • Use a gentle, non-foaming cleanser to avoid stripping the skin of its natural oils.
  • Pat the skin dry gently with a clean, soft towel instead of rubbing.
  • Cover open sores or cracks with a clean bandage or gauze pad.
  • Avoid picking, scratching, or peeling flaky skin, which can create open wounds.
  • Change your sheets, pillowcases, and towels frequently to avoid bacterial buildup.
  • Disinfect high-touch surfaces like doorknobs, phones, and keyboards regularly.

If you notice signs of infection like increased redness, swelling, pain, warmth, oozing, crusting, odor, or fever, contact your dermatologist right away. You may need topical or oral antibiotics to clear the infection and prevent it from spreading.

Seek support.

Dealing with the physical and emotional challenges of TSW can be isolating and overwhelming. It’s important to remember that you are not alone and that support is available. Consider reaching out to:

  • Family and friends who can offer practical and emotional support
  • A mental health professional who can help you cope with the stress and anxiety of TSW
  • Online TSW support communities where you can connect with others going through similar experiences
  • National organizations like the National Eczema Association that provide resources and advocacy for people with eczema and TSW

Joining a support group or talking to a therapist can provide a safe space to express your feelings, learn coping strategies, and find encouragement on your healing journey. Don’t hesitate to ask for help when you need it.

When to Seek Medical Attention

While many people with TSW can manage their symptoms at home with self-care and over-the-counter treatments, there are times when it’s important to seek medical attention. Contact your dermatologist or healthcare provider if you experience:

  • Severe or widespread skin inflammation that is not improving with home treatment
  • Signs of skin infection, such as increased redness, swelling, pain, warmth, oozing, crusting, or fever
  • Intense itching or pain that is interfering with your sleep or daily activities
  • Symptoms of dehydration, such as dark urine, dizziness, rapid heartbeat, or feeling faint
  • Difficulty breathing or swallowing due to skin swelling or inflammation
  • Significant weight loss or malnutrition due to difficulty eating or swallowing
  • Symptoms of depression, anxiety, or other mental health concerns that are impacting your quality of life

Your dermatologist can assess your skin, adjust your treatment plan, and provide guidance on managing your symptoms safely and effectively. They may also refer you to other specialists, such as an allergist, nutritionist, or mental health professional, for additional support.

Remember, TSW is a complex and individualized condition that requires close medical supervision and a personalized approach to treatment. Don’t hesitate to advocate for your health and seek the care and support you need to navigate this challenging journey.


Topical steroid withdrawal is a challenging but treatable condition that can occur when you stop using topical corticosteroids after prolonged or frequent use. While the symptoms of TSW can be uncomfortable and distressing, it’s important to remember that they are a sign of the skin’s natural healing process and not a reflection of permanent damage.

By working closely with a dermatologist to develop a personalized topical steroid withdrawal plan, you can safely and gradually taper off steroid creams while minimizing the risk of severe TSW symptoms. This may involve using alternative therapies like emollients, topical calcineurin inhibitors, and phototherapy to manage inflammation and support skin barrier repair.

In addition to medical treatment, self-care practices like gentle skincare, stress management, and seeking support can be invaluable tools for coping with the physical and emotional challenges of TSW. Remember to be patient with yourself and your skin, as healing is a gradual and non-linear process.

If you’re struggling with TSW, know that you are not alone and that help is available. Don’t hesitate to reach out to your healthcare provider, family and friends, or TSW support communities for guidance and encouragement on your journey to healthier, more resilient skin.

Key Takeaways

  • Topical steroid withdrawal (TSW) is a potential side effect of prolonged or frequent use of topical corticosteroids, especially high-potency steroids on the face or sensitive areas.
  • Symptoms of TSW can include rednessitchingburningflaking, and oozing, which can be mistaken for a worsening of the original skin condition.
  • Weaning off topical steroids under the guidance of a dermatologist can help minimize TSW symptoms while still effectively managing the underlying skin condition.
  • A personalized topical steroid withdrawal plan may involve gradually reducing the potency and frequency of steroid use, using steroid-sparing therapies like emollients and TCIs, and addressing triggers like stress and irritants.
  • Self-care practices like gentle skincare, cool compresses, and relaxation techniques can help manage TSW symptoms and promote skin healing.
  • Seeking support from healthcare providers, family and friends, and TSW communities can be invaluable for coping with the physical and emotional challenges of withdrawal.
  • TSW is a treatable condition that requires patience, persistence, and close medical supervision to navigate successfully.


How long does topical steroid withdrawal last?

The duration of TSW varies from person to person and depends on factors like the potency and duration of steroid use, individual skin characteristics, and overall health. Some people may experience symptoms for a few weeks to a few months, while others may have symptoms that persist for several months to a few years. On average, the healing process can take anywhere from 6 months to 2 years.

Can I use other topical medications during topical steroid withdrawal?

It’s generally recommended to avoid using other topical medications, including over-the-counter creams and ointments, during TSW without first consulting with your dermatologist. Some products may contain ingredients that can further irritate the skin or interfere with the healing process. Your doctor can help you determine which products, if any, are safe and appropriate to use during your withdrawal.

Is topical steroid withdrawal contagious?

No, TSW is not contagious. It is an individual reaction that occurs in the body in response to the discontinuation of topical steroid medications and cannot be spread from person to person.

Can diet affect topical steroid withdrawal?

While there is no specific diet that has been proven to cure or prevent TSW, some people find that making certain dietary changes can help support skin health and reduce inflammation during the withdrawal process. This may include avoiding trigger foods, eating a nutrient-dense diet, and staying hydrated. However, it’s important to work with a healthcare provider or registered dietitian before making significant changes to your diet, as individual nutritional needs and sensitivities can vary.

Are there any long-term effects of topical steroid withdrawal?

In most cases, the skin will fully heal and return to its normal state after completing the TSW process. However, some people may experience long-term changes in skin color, texture, or sensitivity, especially if they used high-potency steroids for an extended period. It’s important to work closely with a dermatologist to monitor your skin’s recovery and address any persistent symptoms or concerns.


  1. Hajar, T., Leshem, Y. A., Hanifin, J. M., Nedorost, S. T., Lio, P. A., Paller, A. S., Block, J., & Simpson, E. L. (2015). A systematic review of topical corticosteroid withdrawal (“steroid addiction”) in patients with atopic dermatitis and other dermatoses. Journal of the American Academy of Dermatology, 72(3), 541-549.e2. https://doi.org/10.1016/j.jaad.2014.11.024
  2. Juhász, M. L. W., Curley, R. A., Rasmussen, A., Malakouti, M., Silverberg, N., & Jacob, S. E. (2017). Systematic Review of the Topical Steroid Addiction and Topical Steroid Withdrawal Phenomenon in Children Diagnosed With Atopic Dermatitis and Treated With Topical Corticosteroids. Journal of the Dermatology Nurses’ Association, 9(5), 233-240. https://doi.org/10.1097/JDN.0000000000000331
  3. Sheary, B. (2018). Topical steroid addiction and withdrawal – An overview for GPs. Australian Family Physician, 47(5), 329-333. https://www.racgp.org.au/afp/2018/may/topical-steroid-addiction-and-withdrawal
  4. Ference, J. D., & Last, A. R. (2009). Choosing topical corticosteroids. American Family Physician, 79(2), 135-140. https://www.aafp.org/afp/2009/0115/p135.html
  5. Siegfried, E. C., Jaworski, J. C., & Hebert, A. A. (2013). Topical calcineurin inhibitors and lymphoma risk: Evidence update with implications for daily practice. American Journal of Clinical Dermatology, 14(3), 163-178. https://doi.org/10.1007/s40257-013-0020-1
  6. Patrizi, A., Raone, B., & Ravaioli, G. M. (2015). Management of atopic dermatitis: Safety and efficacy of phototherapy. Clinical, Cosmetic and Investigational Dermatology, 8, 511-520. https://doi.org/10.2147/CCID.S87987
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