Topical Steroid Withdrawal Treatment: A Comprehensive Guide

June 30, 2024

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If you’ve been using topical corticosteroids to treat a skin condition like eczema or psoriasis, you may have heard of a condition called topical steroid withdrawal (TSW). This occurs when your skin becomes “addicted” to the steroids and flares up when you stop using them. Dealing with TSW can be challenging, but with the right treatment approach, it is possible to heal your skin and regain your quality of life. In this in-depth guide, we’ll cover everything you need to know about treating topical steroid withdrawal effectively.

Understanding Topical Steroid Withdrawal

Topical steroid withdrawal, also known as topical steroid addiction or Red Skin Syndrome, is a condition that can develop when topical corticosteroids are used for prolonged periods or in excessive amounts[1]. The skin becomes dependent on the steroids to control inflammation and when they are discontinued, it rebels with severe redness, itching, burning, swelling and oozing.

TSW is more likely to occur with high-potency steroids used continuously for more than a year[1]. However, it can happen to anyone who uses topical steroids, even if used appropriately under medical supervision. Recognizing the signs of TSW is crucial for getting proper treatment.

Symptoms of Topical Steroid Withdrawal

The symptoms of TSW can be severe and may include[1]:

  • Red, burning, stinging skin
  • Intense itching
  • Oozing and crusting
  • Skin peeling and flaking
  • Edema (swelling)
  • Skin pain and sensitivity
  • Insomnia and fatigue
  • Depression and anxiety

TSW symptoms often appear within days to weeks of discontinuing topical steroids, but can take longer in some cases. They tend to be most severe in the areas where the steroids were applied. TSW is often misdiagnosed as eczema, contact dermatitis, an infection, or even delusions of parasitosis[1].

If you suspect you have TSW, the first step is to consult a dermatologist experienced in treating this condition. They can evaluate your skin, take a thorough history, and create an appropriate treatment plan for your individual needs.

Treating Topical Steroid Withdrawal

While there is no one-size-fits-all approach to treating TSW, the primary goals are to control symptoms, prevent complications, and allow the skin to heal over time. Treatment often requires a multifaceted approach combining medical therapies, skincare adjustments, and lifestyle changes. Here’s what you need to know:

Discontinuing Topical Steroids

The first step in treating TSW is to stop using topical corticosteroids. This allows the skin to begin the healing process. However, discontinuation needs to be done carefully and under the guidance of a dermatologist, as stopping steroids abruptly can worsen TSW symptoms[1].

Your doctor may recommend a tapering schedule for topical steroids to gradually wean your skin off them. This involves using lower potency steroids less frequently over a period of weeks to months. In some cases, a short course of oral steroids may be prescribed to help control severe symptoms during the withdrawal process[1].

It’s important to follow your corticosteroid withdrawal management plan closely and attend all follow-up appointments with your dermatologist. They will monitor your progress and adjust the treatment plan as needed.

Gentle Skincare

As your skin heals from TSW, practicing gentle skincare is essential. Many people find relief with natural remedies for topical steroid withdrawal symptoms like:

  • Moisturizing frequently with fragrance-free, hypoallergenic products
  • Using emollient therapy for topical steroid withdrawal to soothe and protect the skin barrier
  • Applying wet wrap therapy for severe topical steroid withdrawal to hydrate and calm inflamed skin
  • Taking lukewarm baths with gentle, non-soap cleansers
  • Avoiding hot showers, harsh skincare products, and known irritants

Your dermatologist can recommend the best moisturizers for topical steroid withdrawal relief based on your skin type and severity of symptoms. In general, ointments and creams are more effective than lotions for TSW. Ingredients like ceramides, hyaluronic acid, and petrolatum can help restore moisture and repair the skin barrier[2].

Some people also find alternative treatments for topical steroid withdrawal helpful, such as:

  • Acupuncture
  • Herbal medicine
  • Dietary changes
  • Stress reduction techniques

However, it’s crucial to consult your dermatologist before trying any alternative therapies, as some may interact with other treatments or irritate your skin further.

Medications for TSW

In addition to topical treatments, your doctor may prescribe oral medications to help control TSW symptoms. These may include:

  • Antihistamines: Over-the-counter or prescription antihistamines can help relieve itching associated with TSW. Diphenhydramine (Benadryl) or hydroxyzine are commonly used[3].
  • Pain relievers: Over-the-counter acetaminophen or ibuprofen can help control pain and reduce inflammation. Prescription pain medications may be necessary for severe discomfort.
  • Antibiotics: If a secondary bacterial infection develops, oral antibiotics may be needed to clear it up[1].
  • Oral steroids: In severe cases of TSW, a short course of oral corticosteroids like prednisone may be prescribed to control inflammation and allow the skin to heal[1]. However, this must be done cautiously to avoid worsening the steroid withdrawal.
  • Immunosuppressants: Medications that suppress the immune system, such as cyclosporine or methotrexate, may be considered for severe, refractory cases of TSW under close supervision by a dermatologist[1].

Never take any oral medications for TSW without first consulting your doctor, as they can have serious side effects and require careful monitoring.


Phototherapy for topical steroid withdrawal involves controlled exposure to artificial ultraviolet (UV) light to help heal the skin and reduce inflammation. The most common type used for TSW is narrowband UVB phototherapy.

During phototherapy, you stand in a special light box for a prescribed amount of time several times per week. The light helps to:

  • Reduce itching and inflammation
  • Increase vitamin D production
  • Promote skin healing
  • Improve sleep and mood

Phototherapy is usually done in a dermatologist’s office or at a phototherapy center. It requires a significant time commitment and may not be covered by all insurance plans. Potential side effects include burning, aging spots, and an increased risk of skin cancer with long-term use.

Your dermatologist can determine if you are a candidate for phototherapy and create an appropriate treatment schedule. Phototherapy works best for TSW when the skin is no longer oozing or crusting.

Adjunctive Therapies

In addition to medical treatments, there are adjunctive therapies that can help manage TSW symptoms and promote healing. These include:

  • Stress management: TSW can be incredibly stressful and take a toll on your mental health. Engaging in stress-reduction techniques like deep breathing, meditation, yoga, and exercise can help you cope with the challenges of treatment and speed healing[5].
  • Sleep hygiene: Getting enough restful sleep is crucial for skin healing and overall health. Create a cool, dark, comfortable sleep environment and practice good sleep hygiene habits like winding down before bed and avoiding screens.
  • Nutritional support: Eating a healthy, balanced diet rich in skin-supportive nutrients like vitamin C, vitamin D, vitamin E, and omega-3 fatty acids may help promote skin healing[6]. Staying well-hydrated is also important. Ask your doctor if any supplements might be beneficial during TSW treatment.
  • Biofeedback: This technique teaches you to control your body’s physiological responses to stress, which may help reduce inflammation and promote healing. It often involves sensors placed on the skin to monitor things like heart rate, breathing, and skin temperature[7].
  • Counseling: TSW can be an isolating and emotionally challenging experience. Talking to a therapist who understands the condition can help you process difficult emotions, build coping skills, and feel less alone. Ask your dermatologist for a referral or look for a therapist who specializes in working with people with chronic skin conditions.

Lifestyle Modifications

Making certain lifestyle modifications can help support your skin and overall health during TSW treatment:

  • Avoid triggers: Identify and avoid anything that seems to irritate your skin or worsen symptoms, such as certain foods, environmental allergens, harsh skincare products, wool clothing, and excessive heat or sweating.
  • Simplify your skincare routine: Strip your skincare routine down to the basics to avoid irritation. Use lukewarm water, gentle cleansers, and fragrance-free moisturizers. Avoid exfoliating, using harsh toners, or applying multiple products at once.
  • Protect your skin: Always wear sunscreen with an SPF of at least 30 when going outside, even on cloudy days. Wear loose, breathable clothing and avoid scratching or picking at your skin.
  • Manage stress: Chronic stress can worsen inflammation and slow healing. Engage in regular stress management practices like exercise, journaling, deep breathing, and spending time in nature.
  • Stay cool: Heat and sweat can aggravate TSW symptoms. Stay cool by using fans, air conditioning, or cold compresses as needed. Wear light, breathable fabrics and avoid activities that cause overheating.
  • Get support: Surround yourself with understanding friends and family members who can offer practical and emotional support. Consider joining a topical steroid withdrawal support group through the National Eczema Association or online to connect with others going through similar experiences.

Making lifestyle changes can be challenging, but they can make a big difference in managing TSW symptoms and promoting healing. Be patient with yourself and celebrate small victories along the way.

Coping with TSW

Dealing with topical steroid withdrawal can be physically and emotionally exhausting. In addition to working closely with your medical team, it’s important to prioritize self-care and find healthy ways to cope with the challenges of treatment.

Building Resilience

Resilience is the ability to bounce back from difficult experiences. Building resilience can help you weather the ups and downs of TSW treatment and maintain a positive outlook. Some ways to cultivate resilience include[8]:

  • Focusing on what you can control (like your skincare routine and stress management)
  • Practicing gratitude and positive self-talk
  • Staying connected to loved ones
  • Engaging in hobbies and activities that bring you joy
  • Celebrating small victories and progress
  • Learning from setbacks and challenges

If you’re struggling to cope, don’t hesitate to reach out for professional support. Therapy can be a helpful tool for building resilience and processing the emotional impact of TSW.

Seeking Support

TSW can be a lonely and isolating experience, but you don’t have to go through it alone. Connecting with others who understand what you’re going through can provide much-needed support, validation, and encouragement.

Consider joining a topical steroid withdrawal support group through organizations like the National Eczema Association or online forums. These groups provide a safe space to share experiences, ask questions, and get practical tips for managing TSW.

You can also lean on trusted friends and family members for support. Let them know how they can help, whether it’s providing a listening ear, helping with errands, or simply providing a distraction from TSW symptoms.

Remember, seeking support is a sign of strength, not weakness. Surround yourself with people who lift you up and make you feel seen and understood.

Managing Flares

TSW healing is often non-linear, with good days and bad days. During symptom flares, it’s important to have coping mechanisms for the emotional effects of TSW in place. These may include:

  • Practicing deep breathing or meditation
  • Engaging in gentle movement like stretching or yoga
  • Applying a cool compress
  • Distracting yourself with a favorite hobby or activity
  • Listening to soothing music
  • Repeating a calming mantra or affirmation

Remember that flares are temporary and not a sign of failure. Be kind to yourself and focus on small actions you can take to soothe your skin and mind in the moment.

When to See a Doctor

While much of TSW treatment involves self-care and time, there are certain situations where it’s important to see a doctor. Contact your dermatologist if you experience:

  • Severe pain or itching that interferes with daily life
  • Skin infection symptoms like swelling, oozing, or fever
  • Worsening of symptoms despite treatment
  • New symptoms or side effects from medications
  • Difficulty coping with the emotional impact of TSW

It’s also important to have regular check-ins with your dermatologist to monitor your progress and adjust your treatment plan as needed. Finding a dermatologist experienced in TSW can make a big difference in your care and outcomes.

The Road to Healing

Healing from topical steroid withdrawal is a journey that looks different for everyone. Some people may see improvement in a matter of weeks, while others may take months or even years to fully heal. It’s important to be patient with your body and celebrate progress along the way.

As your skin heals, it’s crucial to continue practicing good skincare habits and avoiding triggers. This may involve making long-term changes to your lifestyle and skincare routine. Your dermatologist can provide guidance on how to maintain healthy skin and prevent TSW recurrence.

It’s also important to address any underlying factors that may have contributed to your initial steroid use, such as atopic dermatitis or other skin conditions. Working with your medical team to manage these conditions holistically can help prevent reliance on topical steroids in the future.


How long does it take to heal from topical steroid withdrawal?

The healing timeline for TSW varies from person to person. Some may see improvement in a few weeks, while others may take several months or longer to fully heal. Factors that can affect healing time include the potency and duration of steroid use, individual skin type, and adherence to treatment.

Is there a cure for topical steroid withdrawal?

Currently, there is no cure for TSW. Treatment focuses on managing symptoms, supporting skin healing, and addressing any underlying skin conditions. With time and appropriate care, most people are able to successfully heal from TSW.

Can I use natural remedies to treat topical steroid withdrawal?

Some people find natural remedies like moisturizing, wet wrapping, and stress reduction helpful for managing TSW symptoms. However, it’s important to consult with your dermatologist before trying any new treatments, as some natural remedies may interact with other medications or irritate your skin further. Your dermatologist can provide guidance on which natural remedies may be safe and effective for your individual needs.

Will my skin ever be the same after topical steroid withdrawal?

While TSW can be a challenging and lengthy process, most people are able to achieve healthy, clear skin with time and proper treatment. However, some may experience long-term changes in skin texture, color, or sensitivity. Working closely with your dermatologist can help minimize these long-term effects of topical steroid withdrawal treatment and promote optimal skin health.

How can I prevent topical steroid withdrawal in the future?

Preventing TSW recurrence involves using topical steroids judiciously and under the guidance of a dermatologist. Some strategies for preventing topical steroid withdrawal recurrence include:

  • Using the lowest potency steroid needed to control symptoms
  • Applying steroids intermittently rather than continuously
  • Following a tapering schedule when discontinuing steroid use
  • Using non-steroid treatments to manage skin conditions
  • Practicing good skincare habits and avoiding triggers

Your dermatologist can work with you to develop a personalized plan for maintaining healthy skin after topical steroid withdrawal and minimizing the risk of TSW recurrence.

The Importance of Proper Skincare

As your skin heals from TSW, it’s crucial to practice proper skincare to support the healing process and maintain skin health long-term. This involves:

  • Keeping skin moisturized: Applying fragrance-free, non-comedogenic moisturizers regularly can help soothe irritation, reduce itching, and promote skin barrier repair. Look for products with ingredients like ceramides, hyaluronic acid, and petrolatum.
  • Using gentle cleansers: Harsh soaps and cleansers can strip the skin of its natural oils and worsen TSW symptoms. Choose gentle, pH-balanced cleansers and avoid scrubbing or exfoliating.
  • Protecting skin from the sun: UV exposure can further damage sensitive TSW skin. Apply a broad-spectrum, SPF 30+ sunscreen daily and wear protective clothing when spending time outdoors.
  • Avoiding triggers: Identify and avoid personal triggers that seem to worsen your TSW symptoms. Common triggers include heat, sweat, stress, certain foods, and irritating skincare products.
  • Supporting skin microbiome health: A healthy skin microbiome is crucial for maintaining skin barrier function and preventing infection. Avoid using antibacterial soaps or harsh skincare products that can disrupt the skin microbiome. Consider using products with prebiotics or probiotics to support beneficial skin bacteria[9].

Remember, building a healthy skin microbiome after TSW is a gradual process. Be patient and consistent with your skincare routine, and don’t hesitate to ask your dermatologist for personalized recommendations.

Addressing Misconceptions

There are several common misconceptions about topical steroid withdrawal that can lead to confusion and misinformation. It’s important to separate fact from fiction to ensure proper treatment and support. Here are a few key points to keep in mind:

  • TSW is not a sign of steroid addiction: While the term “topical steroid addiction” is sometimes used interchangeably with TSW, it’s not entirely accurate. TSW is a physiological response to prolonged steroid use, not a true addiction[10]. Understanding the difference between corticosteroid dependence vs addiction is crucial for reducing stigma and ensuring appropriate treatment.
  • TSW is not a rare condition: While the exact prevalence of TSW is unknown, it’s estimated to affect a significant portion of people who use topical steroids long-term[1]. Increased awareness and research are needed to better understand and support those affected.
  • TSW is not a sign of treatment failure: Developing TSW does not mean that topical steroids have failed to treat your skin condition. Rather, it’s a sign that the steroids have been used for too long or at too high of a potency, leading to skin changes. With proper management and time, TSW can be successfully treated.

If you have questions or concerns about TSW, don’t hesitate to talk to your dermatologist or healthcare provider. They can provide accurate information and guidance based on your individual needs and medical history.


Topical steroid withdrawal can be a challenging and overwhelming experience, but with the right treatment approach and support, healing is possible. By working closely with a dermatologist, practicing gentle skincare, and making lifestyle modifications, you can manage TSW symptoms and promote skin healing.

Remember, everyone’s TSW journey is unique, and progress may not always be linear. Celebrate your victories, be patient with setbacks, and lean on your support system when needed.

As you navigate the road to recovery, continue educating yourself about TSW and advocating for your health needs. With time, consistent treatment, and self-compassion, you can achieve healthy, resilient skin and improved quality of life.

Key Points

  • TSW is a complex condition that requires individualized treatment under the guidance of a dermatologist.
  • Treatment may involve topical steroid tapering, gentle skincare, oral medications, phototherapy, and lifestyle modifications.
  • Building a support system and practicing self-care are crucial for managing the physical and emotional challenges of TSW.
  • Healing from TSW is possible with time, patience, and appropriate treatment.
  • Ongoing maintenance and preventive strategies can help prevent TSW recurrence and promote long-term skin health.

If you suspect you may be experiencing symptoms of topical steroid withdrawal, reach out to a dermatologist for evaluation and personalized treatment recommendations. With the right support and care, you can overcome TSW and regain control of your skin health.


  1. Juhász, M. L., Curley, R. A., Rasmussen, A., Malakouti, M., Silverberg, N., & Jacob, S. E. (2017). Systematic Review of the Topical Steroid Addiction and Topical Steroid Withdrawal Phenomenon in Children Diagnosed With Atopic Dermatitis and Treated With Topical Corticosteroids. Journal of the Dermatology Nurses’ Association, 9(5), 233-240.
  2. Ghosh, A., Sengupta, S., Coondoo, A., & Jana, A. K. (2014). Topical corticosteroid addiction and phobia. Indian Journal of Dermatology, 59(5), 465-468.
  3. Fukaya, M., Sato, K., Sato, M., Kimata, H., Fujisawa, S., Dozono, H., Yoshizawa, J., & Minaguchi, S. (2014). Topical steroid addiction in atopic dermatitis. Drug, healthcare and patient safety, 6, 131-138.
  4. Hambly, R., Kirby, B. (2017). The relevance of serum vitamin D in psoriasis: a review. Archives of Dermatological Research, 309, 499–517.
  5. Kannan, S., Heller, M. M., Lee, E. S., & Koo, J. Y. (2011). The role of tumor necrosis factor-alpha and other cytokines in depression: what dermatologists should know. Journal of Dermatological Treatment, 24(2), 148-152.
  6. Katta, R., & Desai, S. P. (2014). Diet and dermatology: the role of dietary intervention in skin disease. The Journal of clinical and aesthetic dermatology, 7(7), 46-51.
  7. Shenefelt P. D. (2010). Psychological interventions in the management of common skin conditions. Psychology research and behavior management, 3, 51-63.
  8. Deckert, S., Kopkow, C., & Schmitt, J. (2014). Nonallergic comorbidities of atopic eczema: an overview of systematic reviews. Allergy, 69(1), 37-45.
  9. Lee, S. Y., Lee, E., Park, Y. M., & Hong, S. J. (2018). Microbiome in the Gut-Skin Axis in Atopic Dermatitis. Allergy, asthma & immunology research, 10(4), 354-362.
  10. Hajar, T., Leshem, Y. A., Hanifin, J. M., Nedorost, S. T., Lio, P. A., Paller, A. S., Block, J., Simpson, E. L., & (the National Eczema Association Task Force) (2015). A systematic review of topical corticosteroid withdrawal (“steroid addiction”) in patients with atopic dermatitis and other dermatoses. Journal of the American Academy of Dermatology, 72(3), 541-549.e2.
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