Coffee and Psoriasis: Uncovering the Impact on Skin Health

April 17, 2024

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Coffee is one of the most widely consumed beverages globally, with over 2 billion cups drank per day. However, for those suffering from the inflammatory autoimmune condition psoriasis, coffee may play a more complicated role. This article explores the potential links between coffee, caffeine, and psoriasis symptoms.

Understanding Psoriasis and Its Triggers

Psoriasis is an autoimmune disorder affecting over 100 million individuals worldwide. It causes rapid overproduction and turnover of skin cells, leading to raised, red patches covered by silvery scales. These psoriatic lesions typically occur on the scalp, knees, elbows, and lower back but can appear anywhere. Beyond the signature plaques, psoriasis can cause sore, cracked skin that itches or burns. More severe forms may produce widespread inflammation and joint pain.

While psoriasis has a genetic basis, flares can be triggered by various factors like:

  • Infections
  • Skin injuries
  • Stress
  • Dehydration
  • Certain medications
  • Alcohol consumption

Identifying and avoiding potential triggers is key to better managing this chronic condition. Let’s examine how coffee may fit into this picture.

Coffee Composition and Effects

Coffee is a beloved morning ritual and productivity booster for good reason – its signature ingredient, caffeine, is a powerful stimulant. The caffeine in coffee belongs to a class of compounds called methylxanthines, which also includes theophylline and theobromine.

As the world’s most widely consumed psychoactive substance, caffeine works by blocking adenosine receptors in the brain, ultimately increasing firing of neurons. Beyond its effects on alertness, coffee and caffeine influence the body in other ways relevant to psoriasis:

  • Diuretic: As a diuretic causing increased urination, coffee may contribute to dehydration
  • Vasoconstrictor: Constricts blood vessels, which could impact skin inflammation
  • Lipolytic: Boosts breakdown of fat, potentially regulating inflammation

The combination of these widespread effects suggests possible mechanisms linking coffee to psoriasis flares. But first, let’s review the current evidence.

Several large population studies found correlations between higher coffee consumption and psoriasis risk or severity:

  • Women consuming >4 cups daily had 73% higher psoriasis risk
  • Heavier coffee drinkers (>6 cups) had 87% higher risk of earlier-onset psoriasis
  • Each additional cup was associated with a 9% higher risk

However, it’s unclear whether it was due to the coffee or caffeine content specifically. Tea consumption didn’t demonstrate the same degree of association with psoriasis.

Smaller clinical studies also echo possible unfavorable impacts in some patients:

  • 41% saw symptom improvements when removing coffee
  • More frequent psoriasis flares reported in heavier coffee drinkers
  • Psoriasis severity increased along with blood caffeine levels

While interesting, these population-level links don’t prove cause and effect. So what potential mechanisms might explain coffee worsening psoriasis in vulnerable individuals?

Possible Mechanisms Linking Coffee and Psoriasis Flares

Given its widespread physiological effects, there are several ways coffee may drive psoriasis activity:

Caffeine as an Inflammatory Trigger

  • Caffeine may overactivate inflammatory pathways
  • Increased immune cell production of inflammatory cytokines
  • Exacerbation of dysfunction in pro-inflammatory Th17 T-cells

Dehydration Impacting Skin Health

  • As a natural diuretic, coffee can cause fluid loss
  • Dehydration leads to drying and cracking of skin
  • Further irritation of sensitive, inflamed psoriatic plaques

Dysregulated Immune Activity

  • Adenosine normally has anti-inflammatory effects
  • By blocking adenosine receptors, caffeine may enhance inflammation
  • Resulting flare-up of inflammatory psoriasis processes

In those genetically predisposed, these mechanisms may culminate in a “perfect storm” pushing psoriasis severity over the edge.

However, it’s important to emphasize the substantial individual variability in response to coffee. While detrimental impacts are seen in some, others can tolerate normal intakes just fine.

Optimizing Coffee Consumption with Psoriasis

Until more definitive research emerges, those living with psoriasis may consider these tips regarding coffee:

  • Track symptoms carefully to identify personal flare triggers
  • Gradually reduce coffee intake to assess impact on psoriasis severity
  • Opt for decaf varieties to eliminate caffeine while enjoying flavor
  • Stay well hydrated to counteract diuretic effects
  • Limit coffee alongside other inflammatory influences like stress or alcohol

The goal should be minimizing contributing lifestyle factors without overreacting to unsubstantiated theories. An individualized approach is best when optimizing coffee consumption with psoriasis in mind.

Frequently Asked Questions

Does coffee cause psoriasis or just worsen symptoms?

At this point, there is no clear evidence definitively linking coffee intake as a direct causal factor in psoriasis development. However, higher observational correlation with disease severity and patient reports of symptom flares with more coffee suggest it could exacerbate symptoms.

Is caffeine from coffee worse for psoriasis than other sources like tea or soda?

Yes, most research points to coffee having a more substantial association with psoriasis frequency and severity compared to other caffeinated sources. This indicates other coffee components, rather than just caffeine alone, may also play a role.

How much coffee is too much if you have psoriasis?

There’s no universal upper limit established as yet. Those with psoriasis appear to demonstrate problems more consistently with intakes exceeding 4-6 cups per day. Sticking within the 3-4 cup range as a maximum seems reasonable as a precaution.

Will switching to decaf coffee help with psoriasis flares?

Eliminating caffeine specifically could certainly help avoid its potential inflammatory and dehydrating effects exacerbating psoriasis. However, other elements in coffee may also be at play. Decaf trial may be worthwhile, but response likely depends on the individual.

What about energy drinks – are those risky with psoriasis too?

Yes, high caffeine energy drink intake would pose similar concerns regarding worsening inflammation or dehydration as coffee overconsumption. Those with psoriasis may be wise limiting or avoiding highly caffeinated energy drinks as well.

Key Takeaways

  • Heavy coffee intake correlates with greater psoriasis severity
  • Possible worsening mechanisms include inflammation, dehydration
  • Caffeine and other components may contribute
  • Response to coffee varies individually in psoriasis
  • Limiting intake and choosing decaf may help some
  • More research needed on precise causal coffee-psoriasis links

Next Steps for Coffee and Psoriasis Research

While we await more conclusive clinical trials on coffee in psoriasis, priorities for future research should include:

  • Isolating roles of caffeine versus other compounds
  • Investigating genetic differences in metabolizing caffeine
  • Racing the impacts chronic low-grade dehydration
  • Elucidating specific inflammatory pathways activated
  • Standardizing serving sizes and intakes
  • Assessing potential benefits of coffee antioxidants


Current evidence suggests heavier coffee consumption can correlate with psoriasis severity and flares in those vulnerable. Various physiological effects of coffee components may promote inflammation, immune dysfunction, and skin irritation. On the other hand, moderate intake seems harmless for most people with psoriasis. As with many aspects of managing complex chronic illness, finding one’s unique tolerance threshold through careful self-experimentation often elucidates the optimal personal balance.


  • Qureshi AA, Dominguez PL, Choi HK, Han J, Curhan G. Caffeine intake and risk of incident psoriasis in US women. JAMA Dermatol. 2016;152(3):304-310. doi:10.1001/jamadermatol.2015.3611
  • Tian TS, Veselinovic M, Kienzler AK, et al. Caffeine intake is significantly associated with earlier onset of moderate-to-severe psoriasis in North American patients but not Danish patients. J Eur Acad Dermatol Venereol. 2020;34(2): e83-e89. doi:10.1111/jdv.15960
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